High-performance liquid chromatograph with an ELSD detector (Electrospray Light Scattering Detector)
Manufacturer: Agilent
Model: 1290 Infinity II
Features
- Organic biomolecule quantitative analyses (sugars, acids, polymers, etc.)
- Simultaneous analysis (variable, depending on the type of analyte)
- Capacity to analyze 1 to 10 samples per hour (99 sample carousel tray)
- Detection limit ranges from 500 ppm to 20 000 ppm depending on the molecule)
- Sensitivity of the device: 1 mAU (diode array detector) and 1 nRIU (refractive index detector)
- Column C3, C8, C18, Amide C-16, NH2, exclusion gel
- Simultaneous double detector: refractive index (sugars) and diode array (UV-visible)
Samples
- Liquids
- Sample size: 0.5 – 1.5 mL
- Injection: 10-50 µL
Examples of applications
- Fermentation bioprocess monitoring (biomolecule production, substrate consumption)
- Monitoring and analysis of organic compounds in membrane filtration processes
- Monitoring and analysis of harmful biomass recycling
- Food component analyses
- Analyses and quantification of the organic impurities of formulations
- Analyses of the effectiveness of nanoparticle treatment on a range of biomolecules